Detalhe da pesquisa
1.
A case study of 10 patients administered HBOC-201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option.
Transfusion
; 60(5): 932-939, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32358832
2.
Use of the blood substitute HBOC-201 in critically ill patients during sickle crisis: a three-case series.
Transfusion
; 58(1): 132-137, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29076161
3.
Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity.
Oncologist
; 21(7): 795-803, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226358
4.
In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles.
Br J Clin Pharmacol
; 80(5): 1122-30, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25907378
5.
Phase I and pharmacokinetic study of trabectedin as a 1- or 3-hour infusion weekly in patients with advanced solid malignancies.
Clin Cancer Res
; 15(10): 3591-9, 2009 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19417019
6.
Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: a phase I, pharmacokinetic, and biological correlative study.
Clin Cancer Res
; 14(23): 7924-9, 2008 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19047123
7.
A phase I and pharmacokinetic study of pemetrexed plus irinotecan in patients with advanced solid malignancies.
Clin Cancer Res
; 13(2 Pt 1): 532-9, 2007 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17255275
8.
Phase I, pharmacokinetic, and biological study of erlotinib in combination with paclitaxel and carboplatin in patients with advanced solid tumors.
Clin Cancer Res
; 12(24): 7406-13, 2006 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17189413
9.
A phase II, pharmacokinetic, and biological correlative study of oblimersen sodium and docetaxel in patients with hormone-refractory prostate cancer.
Clin Cancer Res
; 11(10): 3854-61, 2005 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15897586
10.
Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer.
J Clin Oncol
; 22(15): 3003-15, 2004 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15210739
11.
A phase I and pharmacokinetic study of pegylated camptothecin as a 1-hour infusion every 3 weeks in patients with advanced solid malignancies.
J Clin Oncol
; 21(1): 148-57, 2003 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12506184
12.
Cantuzumab mertansine, a maytansinoid immunoconjugate directed to the CanAg antigen: a phase I, pharmacokinetic, and biologic correlative study.
J Clin Oncol
; 21(2): 211-22, 2003 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12525512
13.
A phase I and pharmacokinetic study of Col-3 (Metastat), an oral tetracycline derivative with potent matrix metalloproteinase and antitumor properties.
Clin Cancer Res
; 10(19): 6512-21, 2004 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15475438
14.
A Phase I and pharmocokinetic study of exatecan mesylate administered as a protracted 21-day infusion in patients with advanced solid malignancies.
Clin Cancer Res
; 9(7): 2527-37, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12855627
15.
Phase I and pharmacokinetic study of the oral fluoropyrimidine S-1 on a once-daily-for-28-day schedule in patients with advanced malignancies.
Clin Cancer Res
; 10(15): 4913-21, 2004 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15297391
16.
A Phase I pharmacokinetic and biological correlative study of oblimersen sodium (genasense, g3139), an antisense oligonucleotide to the bcl-2 mRNA, and of docetaxel in patients with hormone-refractory prostate cancer.
Clin Cancer Res
; 10(15): 5048-57, 2004 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15297406
17.
A phase I and pharmacokinetic study of ILX-295501, an oral diarylsulfonylurea, on a weekly for 3 weeks every 4-week schedule in patients with advanced solid malignancies.
Clin Cancer Res
; 9(15): 5540-9, 2003 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14654534
18.
A Phase I and pharmacokinetic study of squalamine, an aminosterol angiogenesis inhibitor.
Clin Cancer Res
; 9(7): 2465-71, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12855619
19.
A phase I, pharmacokinetic, and biological study of the farnesyltransferase inhibitor tipifarnib in combination with gemcitabine in patients with advanced malignancies.
Clin Cancer Res
; 9(13): 4761-71, 2003 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14581347
20.
Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody.
Int J Radiat Oncol Biol Phys
; 58(3): 984-90, 2004 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14967460